Synthesis and Characterization of DNA/conjugated polymer structures: Toward Molecular Electronics

초록

I will present the synthesis of single organic molecule-bis(micron-sized DNA) triblock supramolecules and the optical and structural characterization of the construct at the single-molecule level. The successful synthesis of the micron-sized DNA-single organic molecule-DNA supramolecule was confirmed by agarose gel electrophoresis with fluorescence imaging under UV excitation. Single triblock structures were directly imaged by combined scanning force microscopy (SFM) and single-molecule fluorescence microscopy, and provided unambiguous confirmation of the existence of the single fluorophore inserted in the middle of the long DNA. This type of triblock structure is a step closer to providing a scaffold for single-molecule electronic devices after metallization of the DNAs.