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Immobilization of Antibody on a Cyclic Olefin Copolymer Surface with Functionalizable, Non-Biofouling Poly[Oligo(Ethylene Glycol) Methacrylate]
- Jeong, Seung Pyo;
- Kang, Sung Min;
- Hong, Daewha;
- Lee, Hee-Yoon;
- Choi, Insung S.;
- ... Ko, Sangwon;
- 외 1명
Citations
WEB OF SCIENCE
6초록
We report a perfluoroaryl azide-based photoreaction for synthesizing functionalizable and nonbiofouling poly[oligo(ethylene glycol) methacrylate] (pOEGMA) films on a chemically inert COC substrate, and an estimation of a surface coverage of the antibody immobilized onto the surface with the immuno-gold nanoparticles. The processes were confirmed by water contact angle measurement, FT-IA spectroscopy, and FE-SEM. The strategy demonstrated in this work could be applied to functionalizations of other polymeric materials and determination of the binding capacity of analytes in biosensors and microfluidic devices.
키워드
Non-Biofouling Polymer; Perfluoroaryl Azide-Based Photopolymerization; MICROFLUIDIC DEVICES; FABRICATION; CHANNELS
- 제목
- Immobilization of Antibody on a Cyclic Olefin Copolymer Surface with Functionalizable, Non-Biofouling Poly[Oligo(Ethylene Glycol) Methacrylate]
- 저자
- Jeong, Seung Pyo; Kang, Sung Min; Hong, Daewha; Lee, Hee-Yoon; Choi, Insung S.; Ko, Sangwon; Lee, Jungkyu K.
- 발행일
- 2015-02
- 유형
- Article
- 권
- 15
- 호
- 2
- 페이지
- 1767 ~ 1770
- 언어
- ENG
- 출판사
- AMER SCIENTIFIC PUBLISHERS
- 발행국가
- 미국
- 분량
- 4 페이지
- ISSN
- E 1533-4899
P 1533-4880